woe, abomination, aching heart, affliction, agony, agony of mind, anguish, atrocity, bad, bale, bane, befoulment, bemoaning, bewailing, bitter cup, bitter draft, bitter pill, bitterness, bleeding heart, blight , broken heart, bugbear, burden, burden of care, calamity, cankerworm of care, care, carking care, cataclysm, catastrophe, corruption, cross, crown of thorns, crushing, crushing burden, crying evil, curse, damage, death, defilement, depression, depth of misery, desolation, despair, despoliation, destruction, detriment, disease, distress, dole, encumbrance, evil, extremity, gall, gall and wormwood, grief, grievance, harm, havoc, heartache, heartbreak, heartfelt grief, heartgrief, heavy heart, hurt, ill, infection, infelicity, infliction, injury, lamentation, languishment, load, melancholia, melancholy, misadventure, mischief, misery, nemesis, open wound, oppression, outrage, pack of troubles, peck of troubles, pest, pestilence, pining, plague, poison, pollution, prostration, regret, rue, running sore, sadness, scourge, sea of troubles, sorrow, sorrowing, suicidal despair , the worst, thorn, torment, toxin, tragedy, trouble, unhappiness, venom, vexation, visitation, waters of bitterness, weight, wretchedness, wrong